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In addition, this patient also had polycythemia, doubtless secondary to high-dose testosterone. The affected person underwent successful percutaneous intervention of the right coronary artery. Physicians and patients ought to be conscious of the scientific penalties of anabolic steroid abuse. Development of an atheromatous plaque perpetuates endothelial dysfunction and promotes platelet aggregation and intracoronary thrombus formation (Ajayi et al 1995; Nieminen et al 1996). Moreover, a component of endothelial dysfunction has been proposed, which may contribute to irregular vessel reactivity. However, testosterone in physiologic doses could even be helpful in sufferers with angina , have larger ischemic thresholds and improved quality of life . Short-term intracoronary administration of testosterone induces coronary artery dilation and will increase coronary blood move in males with established coronary artery disease .
Anabolic Steroids, Acute Myocardial Infarction And Polycythemia: A Case Report And Review Of The Literature
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Discussion And Review Of The Literature
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Effects of testosterone on coronary vasomotor regulation in men with coronary heart illness. Manifestation of severe coronary coronary heart illness after anabolic drug abuse. Relationship between endogenous intercourse hormone ranges, lipoproteins and coronary atherosclerosis in men undergoing coronary angiography. Basaria S, Dobs AS. Risks versus advantages of testosterone therapy in elderly men.
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Acute myocardial infarction in a 22-year-old world class weight lifter utilizing anabolic steroids. Men with coronary artery disease have decrease ranges of androgens than men with normal coronary angiograms. A left anterior oblique view of the proper coronary artery after percutaneous intervention.
Moreover, testosterone has been used within the remedy of reduced muscle mass and bone density as well as anemia. The role testosterone might play in the development of cardiovascular disease has more and more turn into the topic of present interest . Anabolic androgenic steroid use has elevated over the past decade, regardless of its potential for adverse results. Unfortunately, the info on using excessive dose anabolic steroids in humans are primarily supplied as case stories or small studies that lack sufficient control teams.